Ways to Quit Smoking | Clinical Pharmacy and Pharmacology | CURRENTLY

Ways to Quit Smoking |  Clinical Pharmacy and Pharmacology |  CURRENTLY
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Tobacco smoking is the main cause of preventing death, disease, and unemployment in the US.

Quitting smoking will reduce the risk of developing lung cancer, chronic obstructive pulmonary disease, heart disease, and many other chronic diseases. Because of the very addictive nature of nicotine, the rates are very low without treatment. Although treatment plans and procedures can also increase rates of rest, combining these treatments provides the highest success rate for smoking cessation.

Recommended Behavior Media

Effective lifestyle techniques to help people quit smoking include advice from a doctor, nurse, or smoking cessation specialist, individually or in groups. They can also take time out by telephone or through other mobile or app-based media. Some resources include:

  • Phone-based resources

  • Web-based support (see box for more information)

  • Web Messaging software that is available at smokefree.gov/tools-tips/text-programs

  • Smartphone support app like quitSTART National Cancer Institute

Recommended Drugs for Smoking in Nonpregnant Adults

Three drugs have US Food and Drug Administration (FDA) approval for the treatment of smoking dependence: (1) varenicline (expensive); (2) nicotine replacement therapy (transdermal cloth, gum, tablet, inhaler, or nasal spray); and (3) sustained bupropion-hydrochloride released (excited cost).

The standard treatment duration for smoking cessation drugs is 6 to 12 weeks, but tobacco cessation use medications longer than 12 weeks can improve quit rates.

Selection Initial Remedy Governance for Each

The choice of drugs is based on the patient’s preference, underlying medical conditions, and an allergy or intolerance to drugs. In the general population, varenicline appears to be more effective when compared to nicotine replacement therapy or bupropion. Varenicline and nicotine patches used together can increase smoking cessation. The combination of long nicotine-substitution therapies (nicotine scales) with a short form agent (gum, tablet, inspiration, or nasal spray) is more effective than either single-use.

Potential Side Effects

Patients with a replacement may experience nausea, vomiting, and insomnia. Nicotine patches can also cause local skin irritation. The side effects of varenicline may include nausea, headache, fatigue, insomnia, and abnormal nightmares. Bupropion should be avoided in patients with a history of seizures.

Box Section Ref ID

For more information

To find out more about these and other JAMA Patient Pages, go to the Patient Information collection page.

Conflict of Interest Disclosures: no one replies.

Sources: US Preventive Services Task Force. Interventions of tobacco smoking cessation in adults, including pregnant persons. CURRENTLY. 2021 325 (3): 265-279. doi: 10.1001 / jama.2020.25019

Leone FT, Zhang Y, Evers-Casey S, et al. Initiation of tobacco-dependent pharmacology in adults. Am J Respir Crit Care Med. 2020, 202 (2): e5-e31. doi: 10.1164 / rccm.202005-1982ST

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